Prospective, international, multi-center, randomized clinical investigation of TransMedics Organ Care System (OCS LUNG) for lung preservation in transplantation

Goal:

The primary goal is to maintain and support the donor lung at normothermic conditons to minimize damage and ischemic reperfusion injuries. 

Primary endpoint: a composite of patient survival at day 30 post transplantation, and absence of ISHLT Primary Graft Dysfunction Grade 3 in the first 72 (between 0-72 hours) hours post-transplantation. 

Secondary Endpoints:

1. Incidence of ISHLT PGD Grade 3 at 72 hours post transplant.

2. Incidence of ISHLT PGD Grade 2 at 2 or 3 at 72 hours post transplant.

3. Patient survival at day 30.

Investigator(s)

Division(s)

Research Type

Contact Information

Diana Zaldonis
412-647-8723