The Department of Cardiothoracic Surgery prioritizes and views research as a foundational pillar of an academic institution's success. Whether basic, translational, or clinical in nature, our research aims to utilize interdisciplinary modalities and cutting edge methods and technology to help shape the future of cardiothoracic surgery. Our faculty members serve as principal investigators or co-investigators in a myriad of clinical trials, registries, and retrospective studies. The Department prides itself in conducting high quality and high impact research, with the aim of optimizing and revolutionizing patient care and outcomes.
- Cardiac Division
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APOLLO: Transcatheter Mitral Valve Replacement with the Medtronic IntrepidTM TMVR System in patients with severe symptomatic mitral regurgitation
ARTIVION: A ProspEctive, Single ARm, Multi-center Clinical InveStigation to EValuatE the Safety and Effectiveness of AMDS in the TREatment of Acute DeBakey Type I Dissection: PERSEVERE
ABBOTT: Percutaneous MitraClip™ Device or Surgical Mitral Valve REpair in PAtients with PrImaRy Mitral Regurgitation who are Candidates for Surgery (REPAIR MR)
Valved Graft Post-Market Clinical Follow-up Study
TiGER-001 Study
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial (LeAAPS)
A Prospective, Global Study Designed to Collect Real-World Clinical Outcomes of the MITRIS RESILIA Mitral Valve - North America (MOMENTIS)
Terumo Aortic / Thoraflex Hybrid and Relay Extension Post-Approval Study (EXTEND)
Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe, Symptomatic, Aortic Stenosis Requiring Aortic Valve Replacement - ENVISION
ARISE II- Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta
PMCF- Medtronic Cardiac Surgery Post Market Clinical Follow-up Registry
Minimally Invasive coronary surgery compared to STernotomy coronary artery bypass grafting: The MIST Trial
A Prospective, Multi-center, Single-Arm, Open-Label Study of Hearts Transplanted after Non-Ischemic Heart PRESERVation from Extended Donors
- Thoracic Division
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Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Collection of Pleural and Pericardial Fluid for Research
Detection of Genetic Markers of Lung Cancer Initiation and Progression
Esophageal Cancer Risk Registry
Heart, Lung and Esophageal Surgery Institute Research Registry
National Mesothelioma Virtual Bank
Outcomes after Esophagectomy with a Focus on a Minimally Invasive Esophagectomy and Quality of Life
Pathobiology and Gene Expression of Severe Atypical Obstructive Airway Disease
Study of the Immunogenicity of the MUC1 Peptide-Poly-ICLC in Patients with Localized and Locally Advanced Non-Small Cell Lung Cancer
Study to Evaluate Perioperative Circulating Tumor DNA as a Prognostic Biomarker in Patients Undergoing Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer (TSOG 101)
Therapeutic Tumor Microenvironment (TME) Profiling Study
Tumor Neoantigen and Lymphocyte Profiling Study
Utility and Usability of ActivSightTM Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow during Esophageal Surgery in Humans